Herpes Simplex Virus Type 2 ICP47 Inhibits Human TAP but Not Mouse TAP
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چکیده
منابع مشابه
Herpes simplex virus type 2 ICP47 inhibits human TAP but not mouse TAP.
Herpes simplex virus serotype 1 (HSV-1) expresses an immediate-early protein, ICP47, that effectively blocks the major histocompatibility complex class I antigen presentation pathway. HSV-1 ICP47 (ICP47-1) binds with high affinity to the human transporter associated with antigen presentation (TAP) and blocks the binding of antigenic peptides. HSV type 2 (HSV-2) ICP47 (ICP47-2) has only 42% amin...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1998
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.72.3.2560-2563.1998